Drug Standards
Sigma Aldrich Fine Chemicals Biosciences Exemestane for system suitability European Pharmacopoeia (EP) Reference Standard | 107868-30-4 | MFCD00866994 |
Exemestane for system suitability European Pharmacopoeia (EP) Reference Standard | Mol Wt: 296.4 | 107868-30-4 | MFCD00866994 |
![Medchemexpress LLC Phosphonic acid, P-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl] hydrate | 206184-49-8 | MFCD11519982 | 99.5% | C10H16N5O4P·H2O | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000260772.png-250.jpg)
Medchemexpress LLC Phosphonic acid, P-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl] hydrate | 206184-49-8 | MFCD11519982 | 99.5% | C10H16N5O4P·H2O | 10MG
Tenofovir hydrate is an antiviral nucleotide reverse transcriptase inhibitor provided for research use. It is used in studies of HIV and chronic hepatitis B and is supplied as a high-purity white to off-white powder suitable for biochemical and cell-based assays. This product is intended for laboratory research and not for clinical use.
- High purity suitable for research applications.
- White to off-white powder, easy to weigh and dissolve.
- Available as solid, solution in DMSO, or pre-dissolved formats.
- Suitable for biochemical and cell-based antiviral assays.
- Batch-specific certificate of analysis available for validation.
- Intended for research use only; not for human or clinical use.
Medchemexpress LLC Dacomitinib impurity 9 | 2117703-26-9 | 50mg
Dacomitinib impurity 9 is an impurity of Dacomitinib (HY-13272)
Apexbio Technology LLC Cabozantinib malate (XL184) 1140909-48-3 25mg
Cabozantinib malate (XL184 CAS 1140909-48-3) is a small-molecule inhibitor targeting multiple receptor tyrosine kinases notably MET and VEGFR2 with reported IC50 values of 1 3 nM and 0 035 nM respectively It also inhibits additional kinases including RET FLT3 KIT AXL and TEK In cellular assays Cabozantinib shows inhibition of phosphorylation in kinases MET VEGFR2 KIT FLT3 and AXL Moreover Cabozantinib suppresses HMVEC cell-tube formation (IC50 6 7 nM) and attenuates hepatocyte growth factor-induced tumor cell invasion and migration This compound has demonstrated antiproliferative activity in several cancer cell lines supporting its application in oncology research environments
Medchemexpress LLC Phenytoin sodium | 630-93-3 | 99.8% | 1 ML
Phenytoin sodium is a potent blocker of Voltage-gated Na+ channels (VGSCs). It demonstrates antiepileptic activity and has been observed to reduce breast tumor growth and metastasis in mice.
- Potent voltage-gated Na+ channels blocker
- Exhibits antiepileptic activity for partial and generalized tonic-clonic seizures
- Protects against seizures by voltage-dependent block of voltage-gated sodium channels
- Shows low affinity for resting sodium channels
- Greater binding and block occur in depolarized neurons with open/inactivated channels
- Displays strong use-dependent inhibitory potency
- Selectively inhibits pathological hyperexcitability
- Blocks persistent sodium current
- Acts as a Class 1b antiarrhythmic
- Reduces breast tumor growth and metastasis in mice
- Can induce a model of gingival hyperplasia in mice
Sigma Aldrich Fine Chemicals Biosciences Chitosan | 9012-76-4 | MFCD00161512 | 25 g
Chitosan | Purity: ≥75% | 9012-76-4 | MFCD00161512 | 25 g
Sigma Aldrich Fine Chemicals Biosciences S-Allyl-L-cysteine United States Pharmacopeia (USP) Reference Standard | 21593-77-1 | MFCD00151975 | 25MG
S-Allyl-L-cysteine United States Pharmacopeia (USP) Reference Standard | Mol Wt: 161.22 | 21593-77-1 | MFCD00151975 | 25MG
Selleck Chemical LLC Crizotinib (PF-02341066) 5mg 877399-52-5
Crizotinib (PF-02341066) is a potent inhibitor of c-Met and ALK with IC50 of 11 nM and 24 nM in cell-based assays, respectively. It is also a potent ROS1 inhibitor with Ki value less than 0.025 nM. Crizotinib induces autophagy through inhibition of the STAT3 pathway in multiple lung cancer cell lines. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Apexbio Technology LLC Hydrochlorothiazide 58-93-5 10mM (in 1mL DMSO)
Hydrochlorothiazide (CAS 58-93-5) is a small molecule belonging to the thiazide class of diuretics commonly employed in biomedical research for its actions on renal physiology It targets the sodium-chloride symporter in the distal convoluted tubule of the nephron inhibiting sodium and chloride reabsorption This inhibition elevates urinary excretion of sodium chloride and water resulting in increased urine output and reduced blood volume Researchers frequently utilize hydrochlorothiazide in studies focused on fluid homeostasis hypertension management and kidney function regulation
Medchemexpress LLC (±)11(12)-EET-d11 | 2699607-19-5 | 98.0% | 10 UG
(±)11(12)-EET-d11 is a deuterium labeled form of (±)11(12)-EET, functioning as an NLRP3 inflammasome inhibitor. It is used in research for anti-inflammatory, angiogenic, and cardioprotective effects. This compound can serve as a tracer and an internal standard for quantitative analysis by techniques like NMR, GC-MS, or LC-MS.
- Deuterium labeled compound
- Inhibits NLRP3 inflammasome
- Used in anti-inflammatory, angiogenic, and cardioprotective research
- Functions as a tracer
- Serves as an internal standard for quantitative analysis (NMR, GC-MS, LC-MS)
Sigma Aldrich Fine Chemicals Biosciences Zileuton | 111406-87-2 | MFCD00866097 | 10mg
Zileuton | 98% (HPLC) | MW: 236.29 | 111406-87-2 | MFCD00866097 | 10mg
Medchemexpress LLC Naphazoline hydrochloride | 550-99-2 | 99.4% | 10 MM * 1 ML
Naphazoline hydrochloride is a potent α-adrenergic receptor agonist that reduces vascular hyperpermeability and promotes vasoconstriction. It also decreases the levels of inflammatory factors (TNF-α, IL-1β, and IL-6), cytokines (IFN-γ and IL-4), IgE, GMCSF, and NGF. This compound can be used for non-bacterial conjunctivitis research and is intended for research use only, not sold to patients.
- Potent α-adrenergic receptor agonist
- Reduces vascular hyperpermeability and promotes vasoconstriction
- Decreases inflammatory factors (TNF-α, IL-1β, and IL-6)
- Decreases cytokines (IFN-γ and IL-4), IgE, GMCSF, and NGF
- Suitable for non-bacterial conjunctivitis research